Antipsychotic-Induced Rabbit Syndrome in a Pediatric Patient.

R abbit syndrome is an antipsychotic-induced dyskinesia of the mouth, characterized by a fine, rapid, involuntary perioral motion that resembles the chewing motion of a rabbit.1 The oral movements occur in a vertical direction and can be differentiated from tardive dyskinesia by the lack of involvement of the tongue and by the rhythmic pattern.2 However, differentiation of tardive dyskinesia or parkinsonism from rabbit syndrome can remain difficult, as the latter may present with features of the other 2 conditions.1,2 Since it was first described in 1972, rabbit syndrome has been mainly associated with the typical antipsychotics, primarily high-potency agents such as haloperidol.3 However, atypical antipsychotics are now used more frequently than in the past, and rabbit syndrome has also been reported in association with olanzapine, aripiprazole, clozapine, paliperidone, amisulpride, and, most commonly, risperidone.1,2 Here, we report what appears to be the first case of rabbit syndrome in a pediatric patient.